What is Motrin?
Motrin is a nonsteroidal anti-inflammatory drug. It provides the anti-inflammatory, analgesic and febrifugal effect. The mechanism of action is connected with inhibition of prostaglandins synthesis. The drug inhibits the mobility of leukocytes and phagocytosis. Motrin influences immune processes, breaking recognition of specific signals by lymphocytes and thymocytes receptors. The anti-inflammatory effect comes by the end of the first week of treatment.
Is Motrin Ibuprofen?
The main active component of Motrin is Ibuprofen. Motrin is one of the brand names of Ibuprofen. You can whether buy Motrin or Ibuprofen - they are the same drugs. That is why you can save some money and buy generic Motrin, which is cheaper than the brand one.
T drug considerably (up to disappearance) reduces pain syndrome, including joint pains at rest and in motion, increases the volume of movements, reduces morning constraint and swelling of joints.
Motrin is quickly and fully absorbed from the gastrointestinal tract after intake. You can take the drug with your meals, which does not change its bioavailability. The maximum concentration of the drug in blood plasma is reached in 1-2 hours.
Ibuprofen is metabolized by the liver. The elimination half-life is about two hours. Motrin is removed by kidneys generally in a form of inactive metabolites, about 10% - 20% of the drug is removed unchanged.
What does Motrin do? Is Motrin anti-inflammatory and blood thinner? Is Motrin a fever reducer?
Motrin is usually prescribed to treat the following disorders:
- rheumatoid arthritis, including juvenile;
- osteoarthrosis; psoriasis arthritis;
- ankylosing spondylitis;
- acute bursitis, tendinitis, radiculitis, humeroscapular periarteritis;
- decrease easy and moderate pains (in case of injuries of soft tissues);
- headache and toothache;
- excess menstrual blood loss, including women taking intrauterine contraceptive medicine.
Motrin dosage chart. How much of Motrin can I take?
Motrin is available in the following dosages: 200mg, 400mg, 600mg, and Motrin 800 mg pills, as well as oral suspension for babies.
Take 400mg or 600mg of Motrin pills 3-4 times a day in case of osteoarthrosis, psoriasis arthritis, and ankylosing spondylitis.
Take Motrin 800 mg 3 times a day if you have rheumatoid arthritis, the maximum dosage is 2400 mg of Motrin a day.
About 30-40 mg of Motrin on every kg of an adult body weight a day is usually prescribed in case of juvenile rheumatoid arthritis.
Take 400-600mg of Motrin 3-4 times a day if you have tendinitis, bursitis, radiculitis, humeroscapular periarthritis.
If you need to reduce pain in case of injuries to soft tissues (sprains), use 1600-2400 mg of Motrin a day, taking it in several times throughout a day.
Take 1200mg of Motrin a day is case of primary dysmenorrhea.
Take 1600 mg of Motrin a day to reduce excess menstrual blood loss, from the moment of the first bleeding symptoms appearance till their termination, but no longer than 7 days. Avoid taking the drug more than 2 menstrual cycles.
About 1200 mg of Motrin a day is usually prescribed in case of moderate pains.
Motrin side effects
Using Motrin may cause the following side effects:
- stomach ache,
- gastrointestinal tract erosive cankers;
- seldom case of bleedings in gastrointestinal tract;
- some cases reported of insignificant hamaturia, proteinuria and occasionally nephrotic syndrome;
- acute intersticial nephrite;
- possible kidney failure if Motrin is used for a long time;
- decrease in hematocrit and hemoglobin.
Contraindications to use Motrin
Take Motrin with caution, if you have a history of hypersensitivity to ibuprofen, peptic ulcer of stomach and duodenum.
You should also take Motrin under supervision of your doctor if you have pathology of gullet, stomach and duodenum. Consult with your healthcare provider before taking Motrin, if you have kidney disorders. Decrease in Motrin dosages is probable in this case.
There is a great risk of kidneys functioning disorders development for people with kidneys diseases in history, heart failure, liver dysfunction, for the people taking diuretics and for elderly people.
Stop taking Motrin immediately if you have signs of kidney failure.
You should also stop taking the drug if you start experiencing vision disorders. Visit an oculist for consultation to examine definition of the central fields of vision and color perception.
Take Motrin with caution if you have blood clotting disturbances as the drug, being non-steroidal anti-inflammatory medicine, is able to inhibit aggregation of thrombocytes and to extend bleeding time.
Differential diagnosis of pain syndrome can be complicated, because of the febrifugal and anti-inflammatory effect of Motrin.
Controlled clinical studies of using Motrin for children were not conducted.
Can I take Motrin while pregnant?
Is it safe to take Motrin while pregnancy? Actually, it is not recommend to use Motrin during pregnancy, because of its possible adverse effect on a fetus. NSAID drug intake during pregnancy may extend pregnancy and childbirth time.
Is it safe to take Motrin while breastfeeding?
Avoid taking Motrin during breastfeeding.
Motrin overdose. How much of Motrin does it take to overdose?
Most common symptoms of Motrin overdose are:
- gastrointestinal tract disorders;
- vision disorders;
- muscular twitching;
- CNS depression;
- convulsive attacks;
- renal failure;
Motrin overdose treatment.
You should empty stomach by washing it out or induce vomiting in case of acute overdose. Call your doctor if you experience CNS depression or convulsive attacks. As the drug has acid reaction and is removed with urine, use of alkalis is theoretically reasonable. Use absorbent carbon to reduce absorption of Motrin.
Seek immediate medical help if you experience strong overdose symptoms listed above.
There is a possibility of bleeding or ulceration in the gastrointestinal tract several days after overdose. That is why medical supervision is recommended a few days after the overdose.
Can I take Motrin with other medicines like Tramadol, Naproxen, Tylenol etc?
Simultaneous use of opioids or acetylsalicylic acid and Motrin leads to decrease in concentration of Motrin in blood plasma and thus reduction of an anti-inflammatory effect.
Motrin can reduce natriuretic effect of furosemide and thiazide diuretics.
The risk of lithium intoxication development increases, when Motrin is taken with lithium medicine.
Motrin decreases renal canalicular secretion of methotrexate.
According to data from clinical tests, hypoglycemic (antidiabetic) drugs and Motrin interact in minimum degree.
How to buy generic Motrin online?
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