What is Neurontin?
Neurontin represents a group of drugs called antiepileptics. It is very effective to treat epileptic seizures. Neurontin is sometimes used to reduce anxiety and nerve pain. Consult with your attending physician before using the drug.
You can buy Neurontin 300 mg pills as well as 100mg and 600mg pills from an online pharmacy or in your local drugstore.
The main active component of generic Neurontin is gabapentin.
How does Neurontin work?
The action of Neurontin differs from other drugs, which interact with GABA receptors (for example, barbiturates and valproic acid). The drug does not influence GABA metabolism, it reduces the number of calcium ions, which promote developing of neuropathic pain, as well as decreases the death level of certain neurons, making, thus, medicinal impact on a body.
Neurontin is quickly absorbed. The maximum bioavailability (i.e. the amount of active ingredient, which provides an immediate medical effect on a human body) is 60%. The drug is not metabolized and is removed with urine from a body.
What is Neurontin used for?
Neurontin is used to treat epilepsy. The drug is prescribed as a basic therapy medication as well as a part of the combined epilepsy treatment schemes for adults and teenagers.
The medication is effective to treat resistant epilepsy for children of 8-12 years old.
Neurontin is also widely used to treat various neuropathic pains (postherpetic neuralgia, diabetic neuropathy, post-stroke and phantom pains, regional pain syndrome).
The drug can be used both as an independent therapy medication and as an element of a complex treatment.
Neurontin is also used to treat neuropathic pain (only for people over 18 years old).
How to take Neurontin?
Take Neurontin pill after or during your meal with a glass of water.
Take Neurontin 300mg as an initial dosage for adults and teenagers to treat epilepsy.
Increase the drug dosage on 300 mg daily until you achieve the desired clinical effect. Usually, an average effective dosage is reached up to 900-1800 mg of the drug a day. Some people need around 3600 mg of Neurontin a day to reach a positive effect.
The initial dosage of Neurontin for 8-12 years old children is 10-15 mg of the drug on each kg of body weight a day. In the next three days, the effective dosage is increased to 25-30 mg/kg and is divided into 3 daily intakes.
Another scheme Neurontin intake is based on person's actual weight. People with a body weight of 26-36 kg should take 900 mg of the drug a day; people with 37 to 50 kg - 1200 mg of the drug a day; and if body weight exceeds 50 kg - 1800 mg of the drug a day.
It is recommended to take a minimum possible dosage of Neurontin to treat nerve pain. The initial minimum dosage is Neurontin 300 mg a day, which is gradually increased up to 1800 mg a day and divided into 3 daily intakes.
If you are on hemodialysis, take Neurontin 300-400 mg as the initial dosage
Neurontin side effects
The frequency of Neurontin undesirable side effects and their expressiveness is much lower than at other antiсonvulsant drugs
Most common possible side effects are:
- accidental injuries;
- various pains;
- peripheral hypostases;
- weight gain;
- dry mouth;
- abdominal pain;
- gait disorder;
- short wind;
- skin rash;
Possible side effects in case of partial spasms treatment may include:
- viral infection;
- peripheral hypostases;
- weight gain;
- face edema;
- increase in appetite;
- dry mouth or throat;
- nausea and/or vomiting;
- abdominal pain;
- emotional lability;
- muscle twitching;
- strengthening, easing or lack of reflexes;
- skin rash;
- vision disorder;
- urinary tract infections;
- erectile dysfunction.
Contraindication to using Neurontin
Avoid using Neurontin in case of:
- acute pancreatitis;
- young age till 3 years old;
- intolerance of galactose, glucose absorption disturbance, a deficit of lactase;
- hypersensitivity to Neurontin or other drug's components of the drug as well as individual intolerance.
Use Neurontin with caution and under the strict supervision of your doctor in case of:
- renal failure other kidney disorders;
- pregnancy (gabapentin influence on a fetus is still insufficiently studied. Therefore, use the drug only if there are more possible advantages for a mother, than the expected risk for a child);
- breastfeeding ( an active component of the drug is capable of getting into breast milk);
- people of advanced age increased a risk of possible kidney disorders);
- if you have mixed type attacks, including absentia epileptica.
Can I take Neurontin during pregnancy?
You may take the drug only if the expected advantage for a mother justifies possible risk for a fetus.
Can I use Neurontin during breastfeeding?
Neurontin is released into breast milk. Its influence on a baby is not yet known. Thus, it is better to avoid taking the medication during breastfeeding.
Is Neurontin prescribed for children?
Avoid using Neurontin to treat partial spasm for children under 12 years old. It is not recommended to use the drug to treat neuropathic pain for children under 18 years old.
Interaction with other medications
Simultaneous use of Neurontin and morphine increases the pain threshold.
Bioavailability of gabapentin is decreased if it is used together with antacids and astringents.
Avoid using Neurontin together with Cimetidine, as this combination may suppress Neurontin withdrawal with urine.
Simultaneous intake of Neurontin with the oral contraceptives containing Norethisterone and/or ethinylestradiol was not followed by any changes in both drug's action.
Overdose with Neurontin
Most common symptoms of Neurontin overdose are excessive drowsiness, dysarthria, diplopia, dizziness. Disturbances of consciousness were rarely observed.
Neurontin and alcohol
Avoid using Neurontin with alcoholic beverages, as the drug is known as a rather efficient medication to treat alcohol addiction. Their simultaneous use may lead to undesirable side effects and amplify them.
Can Neurontin cause weight gain?
Weight gain is one of the possible side effects during treatment with Neurontin. However, this side effect is quite rare - only around 3% of people, who have used the drug, experienced weight gain. Moreover, this weight gain was rather insignificant.
According to several studies, about 10% of people, who used Neurontin in high dosages, put on weight. Most people haven't noticed any side effects during the study.
There is no clear understanding why Neurontin may cause weight gain. Some possible reasons for this are an increase in appetite, drowsiness, and fatigue (people usually eat more being in these conditions), craving for sweets and carbohydrates, changed hormone levels, reduced metabolism, water retention, etc.
Is Neurontin a controlled substance?
No, the drug is not included in the list of controlled substances. However, you need to have a prescription to buy Neurontin in your local drugstore. It is also possible to get Neurontin online with no RX needed.
Can Neurontin get you high?
Neurontin is not on a list of controlled substances as a narcotic substance. That is why it is unlikely you are going to feel euphoria similar to those after using opioid drugs. However, if you take the medicine in high dosages, you may feel dizziness, drowsiness, low blood pressure.
What should I know before taking Neurontin?
It is recommended to gradually decrease Neurontin dosage withing a week before canceling the drug intake.
The sharp termination of the drug intake in patients with epilepsy provokes convulsive attacks. Neurontin is not used to treat absentia epileptica.
Do not exceed 12 hours interval between two consecutive Neurontin daily intakes. The bioavailability of gabapentin decreases with an increase of its dosage.
Take the drug with caution in case of kidney failure. Your attending medical specialists have to adjust your dosage in this case
Neurontin withdrawal symptom
Though there were no reports of spasms in a case of Neurontin withdrawal syndrome, rapid termination of treatment at people with partial spasms can provoke the development of spasms.
Neurontin is not considered to be an effective medication to treat absence seizure. Increased dosage of the drug may be needed in case of simultaneous therapy with morphine. In this case, it is recommended to have a careful medical examination in terms of the development of such central nervous system (CNS) oppression signs, as drowsiness. In this case, Neurontin or Morphine dosage has to be adequately decreased.
You have to immediately stop treatment and consult with you doctor in case of drowsiness, ataxy, dizziness, increased fatigue, nausea and/or vomiting, weight gain.
You have to be careful when driving a car or doing other potentially dangerous types of activity, demanding increased concentration of attention and speed of psychomotor reactions when taking Neurontin.
Though instruction states that Neurontin does not cause withdrawal syndrome, unpleasant symptoms, such as drowsiness, apathy, unwillingness to do something, suicidal thoughts, irritability are sometimes observed.
Some medical specialists claim that it is impossible to cancel drug intake without medical help.
If you are experiencing any of side effects, contact your healthcare provider in order to adjust your treatment course or to change medication.
You doctor may prescribe you antidepressants to reduce a possibility of side effects in case of Neurontin intake termination. It would be much easier to stop taking the drug with the use of antidepressants.
Advantages of Neurontin:
- it causes side effects less often in comparison with analogs;
- the small list of contraindications;
- it is possible to use the drug in complex therapy;
- low risk of overdose;
- rather cheap Neurontin price.
- probable withdrawal syndrome;
- a risk of depression and suicidal thoughts after its termination;
- negative impact on people, suffering from diabetes mellitus;
- causes acute pancreatitis quite often.
Store the drug in a dry place at room temperature. Do not expose to direct sunlight.
Where to buy Neurontin without a prescription?
You can buy Neurontin online with no prescription required in trusted online pharmacies. The cost of Neurontin depends on whether you buy generic drug or brand medication. Purchase generic Neurontin pills without prescription online, which would be cheaper than in your local pharmacy.