What is Voltaren?
Voltaren is an anti-inflammatory, analgesic and antipyretic drug. It belongs to a group of nonsteroidal anti-inflammatory drugs.
Voltaren generic analog is Diclofenac, which is an active ingredient of the drug. Diclofenac acts to disturb metabolism of arachidonic acid and to decrease synthesis of prostaglandins. A decrease of prostaglandins amount in the center of inflammation causes an analgesic effect of the drug. The decrease of prostaglandins in hypothalamus causes an antipyretic effect.
Using Diclofenac to treat primary dysmenorrhea not only eliminates pain but also considerably reduces blood loss.
Diclofenac is completely absorbed in a bloodstream after intake, however, its action comes not at once as Voltaren tablets are soluble in intestines. The maximum concentration in blood plasma is reached within 2 hours after intake.
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Voltaren starts to act faster if it is used in a form of rectal suppositories. However, an absorption speed of suppositories is less comparing with pills. The maximum concentration of Diclofenac in blood plasma is reached within 1 hour after using a suppository, which contains 50mg of Diclofenac.
Diclofenac has a high extent of linking with plasma proteins. The main part of Diclofenac contacts albumin. The maximum concentration in synovial fluid is higher, than in blood, and remains within 12 hours. However, the transition of Diclofenac into the synovial fluid is slower and the maximum concentration is reached within 2-4 hours after the drug intake.
Voltaren is metabolized by a liver.
The drug elimination half-life is 2-3 hours. Around 60% of Voltaren and its metabolites are removed with urine. The drug is also removed through bile and feces.
Your age and possible diseases, including abnormal liver or kidneys function do not influence absorption, metabolism, and removal of Voltaren.
What is Voltaren used for?
Voltaren is usually prescribed to treat:
- ankylosing spondylitis;
- rheumatoid arthritis, including juvenile;
- backbone pain;
- rheumatic diseases of extraarticular soft tissues;
- gout (Voltaren tablets);
- pain, puffiness, and inflammation of soft tissues and joints as a result of injuries;
- primary dysmenorrhea and other gynecologic diseases which are followed by inflammation and/or pain;
- migraine attacks (only Voltaren in a form of rectal suppositories).
How to take Voltaren?
Take the drug according to a prescription of your attending physician. Only your doctor may determine an individual dosage for you depending on a disease severity.
Take Voltaren tablet after your meals. Swallow it without chewing, wash down with enough water. Do not crush or divide a tablet before intake.
The initial dose of Voltaren for adults is usually 150mg (3 tablets Voltaren 50mg) a day. In case long time treatment or pain syndrome is of average intensity, 75/100mg of Voltaren a day is usually enough.
Divide your daily dosage into several intakes.
If you experience pains at night or morning constraint, use Voltaren rectal suppositories in addition to tablets at night before going to bed. However, do not forget to adjust Voltaren tablets dosage respectively. The total daily Voltaren dosage should exceed 150mg.
Take 50-150mg of Voltaren a day during menstruation periods, depending on pain intensity.
Children of 6 to 15 years should take Voltaren 25 mg tablets. Thus, calculation of dosage is made according to an age and a child's weight. A usual dosage for children from 0,5 to 2mg/kg of body weights a day. This daily dosage should be divided into several intakes.
How to use Voltaren injection solutions?
Voltaren injection solutions are intended for intramuscular use. Avoid using Voltaren injection more than 2 days in a row.
You may combine Voltaren injections with Voltaren tablets. However, the daily dosage still should not be more than 150 mg.
The drug is administered deeply into muscle, in upper outside buttock square. The usual amount of injections is one a day (75 mg of Voltaren).
You may have 2 injections a day with an interval of several hours in case of strong pain. In that case, the second injection is administered in an opposite buttock.
How to use Voltaren rectal suppositories?
Initial dosage for adults is 100-150mg a day. The daily dosage is usually divided into 2-3 intakes. Voltaren rectal suppositories are usually used before going to bed at night if used in a complex with other forms of the drug. A total daily dosage of Voltaren should not exceed 150 mg.
Use 50 to 150 mg of rectal suppositories during menstrual periods depending on the expressiveness of pain and your specific features.
Voltaren rectal suppositories are also used to relieve pain during migraine attacks. Usually, 100mg of Voltaren a day is recommended in this case. You may increase the dosage if needed, but try not to exceed 150 mg of Voltaren a day.
What are side effects of Voltaren?
You may experience the following side effects after Voltaren intake:
- stomach ache;
- appetite loss;
- gastrointestinal bleedings;
- inflammatory diseases of oral cavity and throat (stomatitis, ulitis, glossitis);
- increased level of liver enzymes;
- thorax pains;
- aggravation of symptoms in patients with congestive heart failure;
- orientation in space disorders;
- memory disorders;
- sleep disorders;
- increased fatigue, irritability;
- sudden mood swings;
- there are rare cases of septic meningitis development were reported;
- vision disorder;
- hearing disorders;
- change of mouthfeel;
- skin rash;
- interstitial nephrite;
- papillary necrosis;
- nephrotic syndrome;
- kidney failure (rare);
- development of bronchospasm, anaphylactic reactions up to acute anaphylaxis (rare);
- pneumonitis and vasculitis are observed in some cases.
Local reactions, including hemorrhoids and irritation of rectum mucous membrane, are possible when Voltaren rectal suppositories are used.
Voltaren intake does not influence an ability to drive a care and working with potentially dangerous mechanisms.
If you experience harmful side effects after using Voltaren, report your attending physician about them.
Contraindications to using Voltaren
It is recommended not to use Voltaren if you have:
- an increased individual sensitivity to the drug's components as well as analgene intolerance;
- ulcer of stomach and/or duodenum, gastritis, including erosive, colitis, Crohn's disease;
- hemopoiesis system disorders, obscure etiology;
- third trimester of pregnancy;
- heavy abnormal functions of liver, kidneys or cardiovascular system;
Avoid using Voltaren rectal suppositories if you have hemorrhoids, rectum bleedings, proctitis.
Voltaren is not prescribed for children under 6 years old.
Take Voltaren with caution if you have:
- stomach or duodenum ulcer history;
- history of gastrointestinal bleedings;
- hemostasis disorders;
People of advanced age, especially with low body weight, should also take Voltaren with caution.
Make regular checks of liver, kidneys and peripheral blood if you are using Voltaren for a long time.
May I take Voltaren while pregnant?
Do not take Voltaren if you are in the third trimester of pregnancy. It is considered, that the drug may cause weakness of patrimonial activity and blood flow disorders.
In the first and the second trimesters of pregnancy, Voltaren is prescribed only according to vital indications and in minimal effective doses. Consider the expected advantage of mother and possible risks for a fetus, before taking the drug.
If you need to take Voltaren during lactation, you should consider a possibility to terminate breastfeeding, because Diclofenac is emitted with breast milk and may cause undesirable side effects for a child.
Simultaneous use of Voltaren with methamphetamine may lead to the development of renal failures.
Alcohol, corticotropin and potassium drugs used together with Voltaren increase risk of alimentary system side effects.
Direct or indirect action anticoagulants may increase a risk of intestinal bleedings.
Diclofenac reduces glucose level in blood if used simultaneously with peroral antidiabetic drugs and insulin.
Voltaren may reduce an efficiency of diuretics and antihypertensive drugs. The risk of hyperpotassemia development increases when Voltaren is used together with diuretics. Besides, the risk of urinary system disorders development is also increased.
Simultaneous use of Voltaren with salicylic acid derivatives and other non-steroid anti-inflammatory drugs increases a risk of diclofenac side effects development.
Colchicine promotes digestive tract disorders development.
Co-administration of Voltaren with cardiac glycosides increases a threat of digitalis intoxication.
Diclofenac increases nephrotoxicity of cyclosporine.
Simultaneous use of Voltaren with lithium medicines increase a concentration of lithium in blood.
Antiacid drugs increase the amount of Diclofenac in blood plasma.
Voltaren is not accumulated in a body, therefore chronic overdose is improbable. Common symptoms of acute overdose are nausea, vomiting (sometimes emetic masses with blood), epigastric area pains, spasms and even coma.
If you feel overdose symptoms after using Voltaren, contact your doctor immediately or call an ambulance.
Store the drug in a dry place at room temperature. Do not expose to direct sunlight.
Where can I buy Voltaren online without prescription?
You can purchase Voltaren tablets online with no prescription in the trusted online pharmacy. There is a choice of buying Voltaren generic (Diclofenac generic), which is rather cheap. Or you can buy Voltaren brand at your local pharmacy if you have prescription. It is better to order Voltaren online without prescription from a Canadian or offshore pharmacy.